NCCR

1. Targeted mouse


2. Transgenic mouse
  • Gene :

    prnp gene

     
  • Line name :

    MBP-PrP

     
  • Organ :

    brain

     
  • Cell :

    Oligodendrocytes and Schwann cells

     
  • Feature :

    PrP expression under the control of the murine myelin basic protein (MBP) promoter

     
  • Contact :

    Giger Olivier/ Adriano Aguzzi

     
  • Email :

    olivier.gigerusz.ch

     
  • Phone :

    +41 44 255 27 15

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 17:34

     


3. Transgenic mouse


4. Transgenic mouse
  • Gene :

    prnp gene

     
  • Line name :

    TgN 306 B6, 129Sv-TgN306(IgK), PRNPZH1/ZH1)

     
  • Organ :

    lymphoid organs

     
  • Cell :

    B-cell specific

     
  • Feature :

    B-cell specific expression of PrP on a prnp knockout background (Expression vector pHT4-YK 12 under the control of the Igk promoter)

     
  • Contact :

    Mathias Heikenwälder / Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    montrasio et al. pnas 2001

     
  • Update :

    Monday, 4th July 2005 - 17:34

     


5. Transgenic mouse


6. Transgenic mouse
  • Gene :

    prnp gene

     
  • Line name :

    Tga20 B6, 129Sv-Tga20(phg)PrnpZH1/ZH1

     
  • Organ :

    brain and periphery

     
  • Cell :

    brain and periphery

     
  • Feature :

    Reintroduciton of PrP constructs on prnp knockout background (introduction of half genomic PrP construct (phgPrP) copy number 360

     
  • Contact :

    Petra Schwarz/Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 51

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    fischer m et al., 1996 embo

     
  • Update :

    Monday, 4th July 2005 - 17:42

     


All genes


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