NCCR


1. Transgenic mouse


2. Targeted mouse
  • Gene :

    CNP / Cre

     
  • Line name :

    CNCE

     
  • Organ :

    CNS, low expression also in other organs, like PNS, thymus, testis, heart, Pankreas etc.

     
  • Cell :

    oligodendrocytes

     
  • Feature :

    CNP knock-out and Cre expression under CNP promoter.
    Axonal swellings and neurodegeneration in brain, hydrocephalus and premature death. Unlike other mutants, myelin ultrastructure, periodicity and physical stability are normal.

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:28

     


3. Transgenic mouse
  • Gene :

    Cre

     
  • Line name :

    1950, 2419, 2830 or 2834

     
  • Organ :

    Brain

     
  • Cell :

    Forebrain neurons

     
  • Feature :

    CaMKIIα promoter fused to a Cre gene. Four independent lines yielding distinct patterns of gene recombination (whole forebrain, CA1 specific).

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


4. Transgenic mouse


5. Transgenic mouse


6. Transgenic mouse


7. Transgenic mouse
  • Gene :

    Cre

     
  • Line name :

    CaMKIIalpha promoter - CreER(T2) IRES rtTA2

     
  • Organ :

    forebrain

     
  • Cell :

    neurons

     
  • Feature :

    expresses the tamoxifen inducible Cre recombinase in forebrain neurons, also coexpresses rtTA2 but at a lower level
    several lines available with very similar expression pattern

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.uzh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 23rd March 2009 - 21:19

     


8. Transgenic mouse


9. Transgenic mouse
  • Gene :

    CRE

     
  • Line name :

    B6-MOGiCREtm

     
  • Organ :

    CNS

     
  • Cell :

    Oligodendrocytes

     
  • Feature :

    Cre line for recombination of loxP sites exclusively in MOG expressing cells.
    The MOG-gene is deleted.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     


10. Transgenic mouse



All genes


!!! Dieses Dokument stammt aus dem ETH Web-Archiv und wird nicht mehr gepflegt !!!
!!! This document is stored in the ETH Web archive and is no longer maintained !!!