NCCR


11. Transgenic mouse
  • Gene :

    scn10a-cre

     
  • Line name :

    SNS-Cre

     
  • Organ :

    Peripheral nervous system

     
  • Cell :

    Primary nociceptive neurons

     
  • Feature :

    Mouse expressing cre recombinase in primary nociceptive neurons

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:14

     


12. Transgenic mouse
  • Gene :

    Erythropoietin

     
  • Line name :

    Tg6 TgN(PDGFBEPO)321ZbZ

     
  • Organ :

    brain, testis, lung, plasma

     
  • Cell :

    none

     
  • Feature :

    High hematokrit (0.8 - 0.9).
    Brain: EPO level 26x higher than in wt.
    Plasma: 12 x higher than wt.
    Vasodilation due to increased eNOS

     
  • Contact :

    Max Gassmann

     
  • Email :

    maxgaccess.unizh.ch

     
  • Phone :

    +41 44 635 88 03

     
  • Lab :

    Veterinary Physiology

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 25th July 2005 - 11:55

     


13. Targeted mouse
  • Gene :

    CNP / Cre

     
  • Line name :

    CNCE

     
  • Organ :

    CNS, low expression also in other organs, like PNS, thymus, testis, heart, Pankreas etc.

     
  • Cell :

    oligodendrocytes

     
  • Feature :

    CNP knock-out and Cre expression under CNP promoter.
    Axonal swellings and neurodegeneration in brain, hydrocephalus and premature death. Unlike other mutants, myelin ultrastructure, periodicity and physical stability are normal.

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:28

     


14. Targeted mouse
  • Gene :

    Nex / Cre

     
  • Line name :

    NEXC

     
  • Organ :

    CNS

     
  • Cell :

    neurons

     
  • Feature :

    Cre under the control of the NEX (MATH-2)-promoter and
    knock-out for the bHLH NEX-gene (knock-in mouse)

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Tuesday, 5th July 2005 - 13:11

     


15. Transgenic mouse


16. Transgenic mouse


17. Transgenic mouse


18. Transgenic mouse


19. Transgenic mouse


20. Transgenic mouse
  • Gene :

    CRE

     
  • Line name :

    B6-MOGiCREtm

     
  • Organ :

    CNS

     
  • Cell :

    Oligodendrocytes

     
  • Feature :

    Cre line for recombination of loxP sites exclusively in MOG expressing cells.
    The MOG-gene is deleted.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     



All genes


!!! Dieses Dokument stammt aus dem ETH Web-Archiv und wird nicht mehr gepflegt !!!
!!! This document is stored in the ETH Web archive and is no longer maintained !!!