NCCR


1. Targeted mouse
  • Gene :

    Sox10

     
  • Line name :

    Sox10-/+

     
  • Organ :

    Nervous system

     
  • Cell :

    Neural crest stem cells; oligodendrocytes

     
  • Feature :

    Targeted deletion of the transcription factor Sox10; lacZ knock in

     
  • Contact :

    Lukas Sommer

     
  • Email :

    sommercell.biol.ethz.ch

     
  • Phone :

    +411 633 3349

     
  • Lab :

    Institute of Cell Biology, ETHZ

     
  • Ref. :

    Unpublished

     
  • Update :

    Wednesday, 30th April 2003 - 11:43

     


2. Targeted mouse
  • Gene :

    Nex / Cre

     
  • Line name :

    NEXC

     
  • Organ :

    CNS

     
  • Cell :

    neurons

     
  • Feature :

    Cre under the control of the NEX (MATH-2)-promoter and
    knock-out for the bHLH NEX-gene (knock-in mouse)

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Tuesday, 5th July 2005 - 13:11

     


3. Targeted mouse
  • Gene :

    CNP / Cre

     
  • Line name :

    CNCE

     
  • Organ :

    CNS, low expression also in other organs, like PNS, thymus, testis, heart, Pankreas etc.

     
  • Cell :

    oligodendrocytes

     
  • Feature :

    CNP knock-out and Cre expression under CNP promoter.
    Axonal swellings and neurodegeneration in brain, hydrocephalus and premature death. Unlike other mutants, myelin ultrastructure, periodicity and physical stability are normal.

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:28

     


4. Targeted mouse


5. Transgenic mouse
  • Gene :

    Cre

     
  • Line name :

    1950, 2419, 2830 or 2834

     
  • Organ :

    Brain

     
  • Cell :

    Forebrain neurons

     
  • Feature :

    CaMKIIα promoter fused to a Cre gene. Four independent lines yielding distinct patterns of gene recombination (whole forebrain, CA1 specific).

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


6. Transgenic mouse


7. Transgenic mouse


8. Transgenic mouse


9. Transgenic mouse


10. Transgenic mouse



All genes


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