NCCR


1. Transgenic mouse
  • Gene :

    slc6a5-EGFP

     
  • Line name :

    GlyT2-EGFP

     
  • Organ :

    CNS

     
  • Cell :

    glycinergic neurons

     
  • Feature :

    BAC transgenic mouse expresses EGFP under the transcriptional control of the neuronal glycine transporter gene GlyT2 (i.e. in glycinergic neurons).

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:05

     


2. Transgenic mouse
  • Gene :

    scn10a-cre

     
  • Line name :

    SNS-Cre

     
  • Organ :

    Peripheral nervous system

     
  • Cell :

    Primary nociceptive neurons

     
  • Feature :

    Mouse expressing cre recombinase in primary nociceptive neurons

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:14

     


3. Targeted mouse
  • Gene :

    ptger3

     
  • Line name :

    ptger3tm1sna; EP3 receptor knock-out

     
  • Organ :

    various

     
  • Cell :

    various

     
  • Feature :

    Mouse lacking the EP3 subtype of prostaglandin E2 receptors

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:23

     


4. Targeted mouse
  • Gene :

    ptger2

     
  • Line name :

    ptger2tm1sna; EP2 receptor knock-out

     
  • Organ :

    CNS, kidney etc

     
  • Cell :

    various cell types

     
  • Feature :

    Mouse lacking the EP2 subtype of prostaglandin E2 receptors

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:23

     


5. Transgenic mouse
  • Gene :

    prph1-cre

     
  • Line name :

    tg(prph1-cre)35Don/Mmcd; Peripherin-Cre

     
  • Organ :

    peripheral nervous system

     
  • Cell :

    primary sensory neurons

     
  • Feature :

    Mouse expressing cre recombinase in primary somatosensory neurons

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:23

     


6. Transgenic mouse
  • Gene :

    pnoc-EGFP

     
  • Line name :

    ppN/OFQ-EGFP

     
  • Organ :

    CNS

     
  • Cell :

    neurons expressing pre-pro-nociceptin/orphanin FQ

     
  • Feature :

    BAC transgenic mouse expressing EGFP under the transcriptional control of the pre-pro-nociceptin/orphanin FQ gene.

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Unpublished

     
  • Update :

    Friday, 19th May 2006 - 16:08

     


7. Targeted mouse
  • Gene :

    Pmp22

     
  • Line name :

    Trembler

     
  • Organ :

    PNS

     
  • Cell :

    Schwann cell

     
  • Feature :

    Tr NATURAL MUTANT mice. Asp to Gly point mutation in a putative membrane-associated domain of Pmp22 protein. The autosomal dominant trembler mutation (Tr) maps to mouse chromosome 11. Schwann-cell defect characterized by severe hypomyelination and continued Schwann-cell proliferation throughout life. Results in clumsy movement, tremor and transient seizures at young age.

     
  • Contact :

    Guya Giambonini-Brugnoli

     
  • Email :

    guya.brugnolicell.biol.ethz.ch

     
  • Phone :

    +411 633 3348

     
  • Lab :

    Institute of Cell Biology

     
  • Ref. :

    Abstract

     
  • Update :

    Sunday, 11th May 2003 - 10:33

     


8. Transgenic mouse


9. Targeted mouse
  • Gene :

    Nex / Cre

     
  • Line name :

    NEXC

     
  • Organ :

    CNS

     
  • Cell :

    neurons

     
  • Feature :

    Cre under the control of the NEX (MATH-2)-promoter and
    knock-out for the bHLH NEX-gene (knock-in mouse)

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Tuesday, 5th July 2005 - 13:11

     


10. Transgenic mouse



All genes


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