NCCR


1. Targeted mouse


2. Targeted mouse


3. Transgenic mouse
  • Gene :

    Rag1

     
  • Line name :

    B6.129S7-Rag1tm1Mom/J

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B and T cells

     
  • Feature :

    Homozygotes for targeted null mutations are devoid of mature B and T lymphocytes due to an inability to rearrange their immunoglobulin and T cell receptor genes. Mutants show severe combined immunodeficiency and susceptibility to infections.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     


4. Targeted mouse
  • Gene :

    ptger3

     
  • Line name :

    ptger3tm1sna; EP3 receptor knock-out

     
  • Organ :

    various

     
  • Cell :

    various

     
  • Feature :

    Mouse lacking the EP3 subtype of prostaglandin E2 receptors

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:23

     


5. Targeted mouse
  • Gene :

    ptger2

     
  • Line name :

    ptger2tm1sna; EP2 receptor knock-out

     
  • Organ :

    CNS, kidney etc

     
  • Cell :

    various cell types

     
  • Feature :

    Mouse lacking the EP2 subtype of prostaglandin E2 receptors

     
  • Contact :

    Hanns Ulrich Zeilhofer

     
  • Email :

    zeilhoferpharma.unizh.ch

     
  • Phone :

    +41 44 6355912

     
  • Lab :

    Institute of Pharmacology and Toxicology

     
  • Ref. :

    Abstract

     
  • Update :

    Friday, 19th May 2006 - 16:23

     


6. Zebrafish
  • Gene :

    nn

     
  • Line name :

    zh54

     
  • Organ :

    eye

     
  • Cell :

    unknown

     
  • Feature :

    synaptic transmission between photoreceptors and bipolar cells by ERG measurement

     
  • Contact :

    Stephan Neuhauss

     
  • Email :

    neuhausshifo.unizh.ch

     
  • Phone :

    +411 635 3288

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Wednesday, 12th March 2003 - 09:58

     


7. Transgenic mouse
  • Gene :

    MOG-TcR

     
  • Line name :

    B6-Tg(MOG-TcR)xB6-MOGiCREtm

     
  • Organ :

    Ubiquitous

     
  • Cell :

    T cells,Oligodendrocytes

     
  • Feature :

    These mice express a MOG specific T cell receptor on a MOG -/- background.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:29

     


8. Targeted mouse


9. Transgenic mouse
  • Gene :

    IL-18R

     
  • Line name :

    B6-IL18Rtm

     
  • Organ :

    Ubiquitous

     
  • Cell :

    monocytes and macrophages produce large amounts of various IL18 species

     
  • Feature :

    This mouse is unable to express IL-18 receptor

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:40

     


10. Targeted mouse



All genes


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