NCCR


1. Transgenic mouse
  • Gene :

    Calcineurin

     
  • Line name :

    CN279

     
  • Organ :

    Depends on the line of transactivator (tTA or rtTA) used for crossing

     
  • Cell :

    Forebrain neurons when crossed with CaMKIIα promoter-rtTA mice

     
  • Feature :

    TetO promoter fused to a mouse active calcineurin mutant cDNA.
    Impaired learning, memory and LTP when expressed in forebrain neurons.

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


2. Transgenic mouse
  • Gene :

    Calcineurin inhibitor

     
  • Line name :

    211 (line 5193)

     
  • Organ :

    Depends on the line of transactivator (tTA or rtTA) used for crossing

     
  • Cell :

    Forebrain neurons when crossed with CaMKIIα promoter-rtTA mice

     
  • Feature :

    TetO promoter fused to a mouse calcineurin autoinhibitor peptide cDNA.
    Improved learning, memory and LTP when expressed in forebrain neurons.

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


3. Transgenic mouse
  • Gene :

    Cre

     
  • Line name :

    CaMKIIalpha promoter - CreER(T2) IRES rtTA2

     
  • Organ :

    forebrain

     
  • Cell :

    neurons

     
  • Feature :

    expresses the tamoxifen inducible Cre recombinase in forebrain neurons, also coexpresses rtTA2 but at a lower level
    several lines available with very similar expression pattern

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.uzh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 23rd March 2009 - 21:19

     


4. Transgenic mouse


5. Transgenic mouse
  • Gene :

    Inhibitor-1 (PP1 inhibitor)

     
  • Line name :

    I-1*

     
  • Organ :

    Depends on the line of transactivator (tTA or rtTA) used for crossing

     
  • Cell :

    Forebrain neurons when crossed with CaMKIIα promoter-rtTA mice

     
  • Feature :

    TetO promoter fused to a constitutively active protein phosphatase 1 (PP1) inhibitor cDNA.
    Improved learning and memory when expressed in forebrain neurons.

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


6. Transgenic mouse


7. Transgenic mouse
  • Gene :

    rtTA

     
  • Line name :

    1237

     
  • Organ :

    Brain

     
  • Cell :

    Forebrain neurons

     
  • Feature :

    CaMKIIα promoter fused to the reverse tetracycline-controlled transactivator (rtTA) gene.

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


8. Transgenic mouse


9. Transgenic mouse


10. Transgenic mouse
  • Gene :

    rtTA2

     
  • Line name :

    P0Cx-rtTA2 (693)

     
  • Organ :

    Sciatic nerve / Cerebellum

     
  • Cell :

    Schwann cells

     
  • Feature :

    Doxycycline inducible gene expression in Schwann cells

     
  • Contact :

    Philipp Berger

     
  • Email :

    bergercell.biol.ethz.ch

     
  • Phone :

    +411 633 3341

     
  • Lab :

    Institute of Cell Biology ETH Zürich / Suter Lab

     
  • Ref. :

    Unpublished

     
  • Update :

    Tuesday, 26th August 2003 - 13:53

     



All genes


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