NCCR

1. Targeted mouse
  • Gene :

    Nex / Cre

     
  • Line name :

    NEXC

     
  • Organ :

    CNS

     
  • Cell :

    neurons

     
  • Feature :

    Cre under the control of the NEX (MATH-2)-promoter and
    knock-out for the bHLH NEX-gene (knock-in mouse)

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Tuesday, 5th July 2005 - 13:11

     


2. Targeted mouse
  • Gene :

    CNP / Cre

     
  • Line name :

    CNCE

     
  • Organ :

    CNS, low expression also in other organs, like PNS, thymus, testis, heart, Pankreas etc.

     
  • Cell :

    oligodendrocytes

     
  • Feature :

    CNP knock-out and Cre expression under CNP promoter.
    Axonal swellings and neurodegeneration in brain, hydrocephalus and premature death. Unlike other mutants, myelin ultrastructure, periodicity and physical stability are normal.

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:28

     


3. Targeted mouse
  • Gene :

    MAG

     
  • Line name :

    MAG-KO

     
  • Organ :

    Nervous system

     
  • Cell :

    oligodendrocytes and Schwann cells

     
  • Feature :

    Knock-out for the myelin associated glycoprotein (MAG)

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:28

     


All genes


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