NCCR


11. Targeted mouse
  • Gene :

    prnp

     
  • Line name :

    B6-PrnptmNgsk

     
  • Organ :

    prnp knockout but DpL overexpression

     
  • Cell :

    prnp knockout but Dpl overexpression

     
  • Feature :

    prnp knockout on C57BL/6 background; cerebellar granular degeneration (Dpl overexpression)

     
  • Contact :

    Mathias Heikenwälder

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 11th July 2005 - 18:09

     


12. Transgenic mouse


13. Transgenic mouse


14. Transgenic mouse
  • Gene :

    N-terminal deletion of prnp

     
  • Line name :

    E1931 - B6,129Sv-Tg(delE)1931,PrnpZH1/ZH1

     
  • Organ :

    brain and periphery

     
  • Cell :

    brain and periphery

     
  • Feature :

    N-terminal deletion of prnp (on Prnp background) introduction of constuct pPrPN-term: (sequence encoding AA 68-83 was deleted)

     
  • Contact :

    Mathias Heikenwälder

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 11th July 2005 - 18:04

     


15. Targeted mouse


16. Targeted mouse
  • Gene :

    Lymphotoxin beta receptor

     
  • Line name :

    LtbR-/-

     
  • Organ :

    complete knockout

     
  • Cell :

    complete knockout

     
  • Feature :

    no FDCs; defects in lymphoid moicroarchitecture; no ILNs, no developped MLNs, no PPs;

     
  • Contact :

    Mathias Heikenwälder

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 14:21

     


17. Transgenic mouse


18. Targeted mouse


19. Transgenic mouse


20. Transgenic mouse



All genes


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