NCCR


11. Targeted mouse
  • Gene :

    MyD88

     
  • Line name :

    MyD88-/-

     
  • Organ :

    complete knockout

     
  • Cell :

    complete knockout

     
  • Feature :

    defects in TLR siognalling

     
  • Contact :

    Mathias Heikenwälder / Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 14:27

     


12. Targeted mouse
  • Gene :

    Tlr9

     
  • Line name :

    Tlr9-/-

     
  • Organ :

    complete knockout

     
  • Cell :

    complete knockout

     
  • Feature :

    resistant to CpG-ODN; defects in Tlr9 siganlling

     
  • Contact :

    Mathias Heikenwälder / Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 14:28

     


13. Targeted mouse


14. Targeted mouse


15. Targeted mouse


16. Targeted mouse
  • Gene :

    CD21 and prnp

     
  • Line name :

    CD21-/- prnp-/-

     
  • Organ :

    complete knockout

     
  • Cell :

    complete knockout

     
  • Feature :

    kncokout for CD21 and prnp

     
  • Contact :

    Mathias Heikenwälder / Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 14:37

     


17. Targeted mouse


18. Transgenic mouse
  • Gene :

    Cre-recombinase

     
  • Line name :

    Alb-Cre

     
  • Organ :

    liver

     
  • Cell :

    hepatocytes

     
  • Feature :

    active Cre rekombinase under the Alb-promoter

     
  • Contact :

    Mathias Heikenwälder / Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 14:51

     


19. Transgenic mouse
  • Gene :

    Lymphotoxin alpha

     
  • Line name :

    RIP-LTa

     
  • Organ :

    pancreas and kidney

     
  • Cell :

    beta pancreatic cells and proximal tubules

     
  • Feature :

    ectopic tertiary follicles in pancreas and kidney

     
  • Contact :

    Mathias Heikenwälder / Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 14:59

     


20. Targeted mouse
  • Gene :

    Interleukin 10

     
  • Line name :

    IL10-/-

     
  • Organ :

    complete knockout

     
  • Cell :

    complete knockout

     
  • Feature :

    lack of IL10 expression; CD like inflammation in the gut

     
  • Contact :

    Mathias Heikenwälder / Adriano Aguzzi

     
  • Email :

    mathias.heikenwaelderusz.ch

     
  • Phone :

    +41 44 255 21 06

     
  • Lab :

    Inst. for Neuropathology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 4th July 2005 - 15:05

     



All genes


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