NCCR


21. Targeted mouse


22. Targeted mouse


23. Targeted mouse
  • Gene :

    MAG

     
  • Line name :

    MAG-KO

     
  • Organ :

    Nervous system

     
  • Cell :

    oligodendrocytes and Schwann cells

     
  • Feature :

    Knock-out for the myelin associated glycoprotein (MAG)

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:28

     


24. Targeted mouse


25. Targeted mouse


26. Targeted mouse


27. Targeted mouse
  • Gene :

    Nex / Cre

     
  • Line name :

    NEXC

     
  • Organ :

    CNS

     
  • Cell :

    neurons

     
  • Feature :

    Cre under the control of the NEX (MATH-2)-promoter and
    knock-out for the bHLH NEX-gene (knock-in mouse)

     
  • Contact :

    Leda Dimou

     
  • Email :

    dimouhifo.unizh.ch

     
  • Phone :

    +41 44 635 3256

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Tuesday, 5th July 2005 - 13:11

     


28. Targeted mouse
  • Gene :

    Nogo-A

     
  • Line name :

    Nogo-A KO

     
  • Organ :

    CNS

     
  • Cell :

    mainly oligodendrocytes and neurons

     
  • Feature :

    Conventional knockouts of the myelin neurite outgrowth inhibitor Nogo-A
    Back-crossed into the C57Bl/6 and the Sv129 background

     
  • Contact :

    Martin Schwab

     
  • Email :

    schwabhifo.unizh.ch

     
  • Phone :

    +41 44 635 3330

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:30

     


29. Targeted mouse


30. Targeted mouse
  • Gene :

    Pmp22

     
  • Line name :

    Pmp22 KO

     
  • Organ :

    PNS

     
  • Cell :

    Schwann cell

     
  • Feature :

    Retarded onset of myelination, abundant sausage-like hypermyelination structures (tomacula) at a young age followed by severe demyelination, axonal loss and functional impairment. Mice carrying one functional copy of Pmp22 are less affected but also exhibit focal tomacula comparable morphologically to those in hereditary neuropathy with liability to pressure palsies (HNPP).

     
  • Contact :

    Guya Giambonini-Brugnoli

     
  • Email :

    guya.brugnolicell.biol.ethz.ch

     
  • Phone :

    +411 633 3348

     
  • Lab :

    Institute of Cell Biology

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 30th April 2003 - 11:21

     



All genes


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