NCCR


1. Transgenic mouse


2. Transgenic mouse


3. Transgenic mouse


4. Transgenic mouse
  • Gene :

    Calcineurin

     
  • Line name :

    CN279

     
  • Organ :

    Depends on the line of transactivator (tTA or rtTA) used for crossing

     
  • Cell :

    Forebrain neurons when crossed with CaMKIIα promoter-rtTA mice

     
  • Feature :

    TetO promoter fused to a mouse active calcineurin mutant cDNA.
    Impaired learning, memory and LTP when expressed in forebrain neurons.

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


5. Transgenic mouse
  • Gene :

    Calcineurin inhibitor

     
  • Line name :

    211 (line 5193)

     
  • Organ :

    Depends on the line of transactivator (tTA or rtTA) used for crossing

     
  • Cell :

    Forebrain neurons when crossed with CaMKIIα promoter-rtTA mice

     
  • Feature :

    TetO promoter fused to a mouse calcineurin autoinhibitor peptide cDNA.
    Improved learning, memory and LTP when expressed in forebrain neurons.

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


6. Transgenic mouse


7. Transgenic mouse
  • Gene :

    CD11c-DTR

     
  • Line name :

    B6-Tg(CD11c-DTR-eGFP)

     
  • Organ :

    Ubiquitous

     
  • Cell :

    Dendritic cells

     
  • Feature :

    Inducible depletion of DC with diphtheria toxin

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:23

     


8. Transgenic mouse
  • Gene :

    CD11c-MHII

     
  • Line name :

    B6-Tg(CD11c-IABb)xB6-IABbtm

     
  • Organ :

    Ubiquitous

     
  • Cell :

    Dendritic cells

     
  • Feature :

    Selective expression of the MHCII complex on DC in a MHCII -/- background

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:02

     


9. Transgenic mouse
  • Gene :

    CD40

     
  • Line name :

    B6.129P2-Tnfrsf5tm1Kik/J

     
  • Organ :

    Ubiquitous

     
  • Cell :

    CD40 protein is expressed on all B-lymphocytes during various stages of development, activated T-cells and monocytes, follicular dendritic cells, thymic epithelial cells.

     
  • Feature :

    Germinal center centrocytes are prevented from undergoing cell death by apoptosis by activation through CD40 and antigen receptors.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 15:57

     


10. Transgenic mouse
  • Gene :

    Cre

     
  • Line name :

    1950, 2419, 2830 or 2834

     
  • Organ :

    Brain

     
  • Cell :

    Forebrain neurons

     
  • Feature :

    CaMKIIα promoter fused to a Cre gene. Four independent lines yielding distinct patterns of gene recombination (whole forebrain, CA1 specific).

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     



All genes


!!! Dieses Dokument stammt aus dem ETH Web-Archiv und wird nicht mehr gepflegt !!!
!!! This document is stored in the ETH Web archive and is no longer maintained !!!