NCCR


21. Transgenic mouse


22. Transgenic mouse
  • Gene :

    Erythropoietin

     
  • Line name :

    Tg6 TgN(PDGFBEPO)321ZbZ

     
  • Organ :

    brain, testis, lung, plasma

     
  • Cell :

    none

     
  • Feature :

    High hematokrit (0.8 - 0.9).
    Brain: EPO level 26x higher than in wt.
    Plasma: 12 x higher than wt.
    Vasodilation due to increased eNOS

     
  • Contact :

    Max Gassmann

     
  • Email :

    maxgaccess.unizh.ch

     
  • Phone :

    +41 44 635 88 03

     
  • Lab :

    Veterinary Physiology

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 25th July 2005 - 11:55

     


23. Transgenic mouse


24. Transgenic mouse
  • Gene :

    FcR(gamma)

     
  • Line name :

    B6.129P2-Fcerg1tm1Rav

     
  • Organ :

    Ubiquitous

     
  • Cell :

    macrophages, neutrophils, mast cells, basophils and NK cells

     
  • Feature :

    Fcer1g knockout mice are deficient in the gamma chain subunit of the FcgammaRI, FcgammaRIII and FcepsilonRI receptors. The deleted gamma chain subunit is essential for cell surface expression of these molecules.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    eur j immunol (1994) 25(7): 2107-2110.

     
  • Update :

    Monday, 15th November 2004 - 16:36

     


25. Transgenic mouse
  • Gene :

    FcR(gamma),IgH

     
  • Line name :

    B6.129P2-Fcerg1tm1Rav x B6-IgHtm1Mom

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B cells

     
  • Feature :

    This mice are deficient in the gamma chain subunit of the FcgammaRI, FcgammaRIII and FcepsilonRI receptors and they are unable to produce functional Ab's.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     


26. Transgenic mouse


27. Transgenic mouse


28. Transgenic mouse


29. Transgenic mouse


30. Transgenic mouse



All genes


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