NCCR


31. Transgenic mouse
  • Gene :

    hGFAP-CreER(T2)

     
  • Line name :

    GCTF

     
  • Organ :

    Brain

     
  • Cell :

    Astrocytes

     
  • Feature :

    hGFAP promoter fused to tamoxifen-dependent CreER(T2) recombinase. Generously provided by Frank Kirchhoff, Göttingen

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


32. Transgenic mouse


33. Transgenic mouse
  • Gene :

    IgH

     
  • Line name :

    B6-IgHtm1Mom

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B cells

     
  • Feature :

    No functional Ab's

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     


34. Transgenic mouse
  • Gene :

    IL-12p35

     
  • Line name :

    B6;IL-12p35tm/J

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B and T cells

     
  • Feature :

    The IL-12 is a heterodimeric 70 kDa glycoprotein (IL12-p70 ) consisting of a 40 kDa subunit and a 35 kDa subunit.
    The p35 supunit is knock-out.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:40

     


35. Transgenic mouse
  • Gene :

    IL-18

     
  • Line name :

    B6-IL18tm

     
  • Organ :

    Ubiquitous

     
  • Cell :

    monocytes and macrophages produce large amounts of various IL18 species

     
  • Feature :

    This mouse is unable to express IL-18

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:40

     


36. Transgenic mouse
  • Gene :

    IL-18R

     
  • Line name :

    B6-IL18Rtm

     
  • Organ :

    Ubiquitous

     
  • Cell :

    monocytes and macrophages produce large amounts of various IL18 species

     
  • Feature :

    This mouse is unable to express IL-18 receptor

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:40

     


37. Transgenic mouse
  • Gene :

    IL-22 (IL-TIF)

     
  • Line name :

    B6-IL22tm

     
  • Organ :

    IL-TIF is expressed constitutively in thymus and brain.

     
  • Cell :

    thymic lymphomas, T-cells, and mast cells, and in freshly isolated splenocytes

     
  • Feature :

    No IL-22

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:40

     


38. Transgenic mouse
  • Gene :

    IL12p40

     
  • Line name :

    B6;IL-12p40tm/J

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B and T cells

     
  • Feature :

    The IL-12 is a heterodimeric 70 kDa glycoprotein (IL12-p70 ) consisting of a 40 kDa subunit and a 35 kDa subunit.
    p40 has been shown to be a subunit of another composite cytokine, designated IL23 .
    The p40 supunit is knock-out.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:40

     


39. Transgenic mouse
  • Gene :

    Inhibitor-1 (PP1 inhibitor)

     
  • Line name :

    I-1*

     
  • Organ :

    Depends on the line of transactivator (tTA or rtTA) used for crossing

     
  • Cell :

    Forebrain neurons when crossed with CaMKIIα promoter-rtTA mice

     
  • Feature :

    TetO promoter fused to a constitutively active protein phosphatase 1 (PP1) inhibitor cDNA.
    Improved learning and memory when expressed in forebrain neurons.

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


40. Transgenic mouse



All genes


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