NCCR


51. Transgenic mouse


52. Transgenic mouse


53. Transgenic mouse


54. Transgenic mouse


55. Transgenic mouse
  • Gene :

    Neurotrophin

     
  • Line name :

    K14NGF

     
  • Organ :

    Epidermis and lymphoid organs

     
  • Cell :

    Keratinocytes

     
  • Feature :

    Overexpression of NGF in the skin causes hypertrophy of sensory nerves in skin and sympathetic nerves in lymphoid organs

     
  • Contact :

    Markus Glatzel

     
  • Email :

    markus.glatzelusz.ch

     
  • Phone :

    +411 255 2849

     
  • Lab :

    Institute of Neuropathology

     
  • Ref. :

    j neurosci. 1994 mar;14(3 pt 2):1422-32.

     
  • Update :

    Tuesday, 5th August 2003 - 15:47

     


56. Transgenic mouse
  • Gene :

    NIK

     
  • Line name :

    B6.AEj-Aly

     
  • Organ :

    Ubiquitous

     
  • Cell :

    Ubiquitous

     
  • Feature :

    Alymphoplasie

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:13

     


57. Transgenic mouse


58. Transgenic mouse
  • Gene :

    NogoA

     
  • Line name :

    pBI-11 and pBI-13

     
  • Organ :

    PNS

     
  • Cell :

    Schwann Cells

     
  • Feature :

    myc-tagged Nogo-A and b-Galactosidase expressed under the control of the bidirectional tetO-promoter (pBI-3 construct, Baron et al., 1995)

     
  • Contact :

    Martin Schwab

     
  • Email :

    schwabhifo.unizh.ch

     
  • Phone :

    +41 44 635 3330

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Wednesday, 6th July 2005 - 12:30

     


59. Transgenic mouse


60. Transgenic mouse
  • Gene :

    Pmp22

     
  • Line name :

    Pmp22 Tg

     
  • Organ :

    PNS

     
  • Cell :

    Schwann cell

     
  • Feature :

    Mice carrying 16-30 copies of the pmp22 gene have severe congenital hypomyelinating neuropathy with an almost complete lack of myelin and marked slowing of nerve conduction. Affected nerves have more nonmyelinating Schwann cells not forming onion bulbs but aligning in association with axons. Mutant Schwann cells adopt a premyelination-like state (express embryonic markers). Continued Schwann cell proliferation into adulthood.

     
  • Contact :

    Guya Giambonini-Brugnoli

     
  • Email :

    guya.brugnolicell.biol.ethz.ch

     
  • Phone :

    +411 633 3348

     
  • Lab :

    Institute of Cell Biology

     
  • Ref. :

    Abstract

     
  • Update :

    Sunday, 11th May 2003 - 10:26

     



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