NCCR


31. Transgenic mouse


32. Transgenic mouse
  • Gene :

    Zif268 (Egr-1)

     
  • Line name :

    bitetO-lacZ/Zif268

     
  • Organ :

    according to the (r)tTA inducer line

     
  • Cell :

    according to the (r)tTA inducer line

     
  • Feature :

    coexpression of lacZ reporter and Zif268
    with CaMKIIalpha promoter-rtTA2 line expression in forebrain neurons

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.uzh.ch

     
  • Phone :

    +41 44 635 33 60

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Abstract

     
  • Update :

    Monday, 23rd March 2009 - 21:19

     


33. Transgenic mouse
  • Gene :

    hGFAP-CreER(T2)

     
  • Line name :

    GCTF

     
  • Organ :

    Brain

     
  • Cell :

    Astrocytes

     
  • Feature :

    hGFAP promoter fused to tamoxifen-dependent CreER(T2) recombinase. Generously provided by Frank Kirchhoff, Göttingen

     
  • Contact :

    Isabelle Mansuy

     
  • Email :

    mansuyhifo.unizh.ch

     
  • Phone :

    +41 44 635 3360

     
  • Lab :

    Brain Research Institute

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 23rd July 2007 - 15:28

     


34. Transgenic mouse


35. Transgenic mouse
  • Gene :

    FcR(gamma),IgH

     
  • Line name :

    B6.129P2-Fcerg1tm1Rav x B6-IgHtm1Mom

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B cells

     
  • Feature :

    This mice are deficient in the gamma chain subunit of the FcgammaRI, FcgammaRIII and FcepsilonRI receptors and they are unable to produce functional Ab's.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     


36. Transgenic mouse
  • Gene :

    Rag1

     
  • Line name :

    B6.129S7-Rag1tm1Mom/J

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B and T cells

     
  • Feature :

    Homozygotes for targeted null mutations are devoid of mature B and T lymphocytes due to an inability to rearrange their immunoglobulin and T cell receptor genes. Mutants show severe combined immunodeficiency and susceptibility to infections.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     


37. Transgenic mouse
  • Gene :

    IgH

     
  • Line name :

    B6-IgHtm1Mom

     
  • Organ :

    Ubiquitous

     
  • Cell :

    B cells

     
  • Feature :

    No functional Ab's

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 17:07

     


38. Transgenic mouse
  • Gene :

    IL-22 (IL-TIF)

     
  • Line name :

    B6-IL22tm

     
  • Organ :

    IL-TIF is expressed constitutively in thymus and brain.

     
  • Cell :

    thymic lymphomas, T-cells, and mast cells, and in freshly isolated splenocytes

     
  • Feature :

    No IL-22

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:40

     


39. Transgenic mouse
  • Gene :

    FcR(gamma)

     
  • Line name :

    B6.129P2-Fcerg1tm1Rav

     
  • Organ :

    Ubiquitous

     
  • Cell :

    macrophages, neutrophils, mast cells, basophils and NK cells

     
  • Feature :

    Fcer1g knockout mice are deficient in the gamma chain subunit of the FcgammaRI, FcgammaRIII and FcepsilonRI receptors. The deleted gamma chain subunit is essential for cell surface expression of these molecules.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    eur j immunol (1994) 25(7): 2107-2110.

     
  • Update :

    Monday, 15th November 2004 - 16:36

     


40. Transgenic mouse
  • Gene :

    MOG-TcR

     
  • Line name :

    B6-Tg(MOG-TcR)xB6-MOGiCREtm

     
  • Organ :

    Ubiquitous

     
  • Cell :

    T cells,Oligodendrocytes

     
  • Feature :

    These mice express a MOG specific T cell receptor on a MOG -/- background.

     
  • Contact :

    Burkhard Becher

     
  • Email :

    burkhard.becherusz.ch

     
  • Phone :

    +411 255 8842

     
  • Lab :

    Neuroimmunology

     
  • Ref. :

    Unpublished

     
  • Update :

    Monday, 15th November 2004 - 16:29

     



All genes


!!! Dieses Dokument stammt aus dem ETH Web-Archiv und wird nicht mehr gepflegt !!!
!!! This document is stored in the ETH Web archive and is no longer maintained !!!